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NOW Raises Concerns About Phosphatidyl Serine Supplements Purchased on Amazon.com

by Nicholas Saraceno | September 9, 2020

Following NOW’s (Bloomingdale, IL) report earlier this year of CoQ10, acetyl-l-carnitine and SAMe supplements with alarming quality and labeling problems sold on Amazon, NOW has identified similar serious failings in the phosphatidyl serine (PS) category, the company stated.

NOW purchased and tested a group of PS products on Amazon, choosing this particular supplement for several key reasons. According to SPINS data, NOW is the leading seller of PS in natural food stores, and the company knows the product well. NOW staff noticed that its PS sales were declining on Amazon, and investigated. NOW found that the top selling brands on Amazon were offering prices that averaged 70 percent below NOW’s already discounted prices. Knowing that the prices looked “too-good-to-be-true,” it made sense to test and verify potencies. Because PS is an expensive supplement, the incentive is high for marketing brands to put extra funds into Amazon-sponsored fees. NOW had previously tested examples in this and other categories and found these semi-private label brands sold exclusively on Amazon to display faulty labeling and be of poor quality. When most quality brands sell 100 mg PS as the standard potency, it’s questionable to see high potencies such as 400 mg or 500 mg.

NOW’s initial analysis of simply reading label information found multiple problems. PS is a complicated supplement, which makes it easier to have confusion. Many of the brands included in this report list a high potency, such as 500 mg, on the front label (and Amazon’s keyword) panel, yet the side panel often states that amount per 2 or 3 capsules.  Others were more deceptive by adding things such as “Phosphatidyl Serine Complex” in order to show a high potency value, even when the actual potency of PS would only be 20 percent of that number.  Here are some examples:

Absonutrix is deceptively labeled as “Phosphatidylserine Complex 500 mg”
Naturebell is deceptively labeled as “Phosphatidylserine 20% 400 mg per 2 Cap serving”.

Havasu brand also labels this way “Phosphatidyl Serine 20% 100 mg”

longlifenutri is mislabeled as “Phosphatidylserine 500 mg (per 2 caps) (standardized to 20%)”
NUSA brand label is unclear how much PS is in each capsule
Both Earth Natural brands mislabel listing PS as 500 mg on the front, but only 50 mg per cap on the side fine print
Correct labeling should be “Phosphatidyl Serine 100 mg (from 500 mg Sunflower/Soy Lecithin Complex)” if the raw ingredient is 20% PS from Complex, or simply “Phosphatidyl Serine….100 mg”.

A total of 43 samples were purchased on Amazon, generally three bottles of each brand, and tested to verify results.  Three of these were NOW brand and results on these were 100 to 108 percent of label claims. Of the remaining non-NOW brands, two samples were discarded when results revealed 2.5 times the label potency claim so it was suspected these products were spiked with added Serine in order to fool testing. Two samples passed potency (not included in this report), while 36 samples failed. Of the 36 failures, 17 of these products contained less than 10 percent of the labeled value.

“That’s a shockingly poor failure rate, but not really a surprise based upon our previous experience testing supplements sold on Amazon,” said Dan Richard, vice president of global sales and marketing. “Amazon has to find a way to raise the bar on products they sell, especially today with people buying more supplements from Amazon in order to stay healthy.”

The results are reported in the chart below, which NOW tested by HPLC both by their in-house labs and independently at Eurofins Labs.

Phosphatidyl Serine Assay Results May – July 2020 from Amazon Purchases April 3, 2020 & May 27, 2020    
Brand Phosphatidyl Serine on Amazon Count Lot # Exp. Date Label Claim per Cap Results per Cap Lab Test % Label Claim
NOW Foods 60 Vcaps 3138361 Dec-21 100mg 104.4 mg NOW 104%
NOW Foods 120 Vcaps 3146319 Feb-22 100mg 100.8 mg NOW 100%
NOW Foods 120 Vcaps 3146319 Feb-22 100mg 108 mg Eurofins 108%
Absonutrix (mislabeled*) 120 Vcaps AS101918-1 Oct-21 520mg 2 mg NOW < 2%
Absonutrix (mislabeled*) 120 Vcaps AS101918-1 Oct-21 520mg 5.3 mg NOW < 2%
Absonutrix (mislabeled*) 120 Vcaps AS101918-1 Oct-21 520mg 5.8 mg Eurofins < 2%
BoostCeuticals (+ Formula) 100 Caps 5121926 Mar-24 167mg 12.8 mg NOW 8%
BoostCeuticals (+ Formula) 100 Caps 27012004 Feb-24 167mg 57 mg Eurofins 34%
Doublewood Supplements 120 Caps 1912697 Jan-23 150mg 67.4 mg NOW 45%
Doublewood Supplements 120 Caps 1912697 Jan-23 150mg 48.1 mg NOW 32%
Doublewood Supplements 120 Caps 1912697 Jan-23 150mg 24.3 mg Eurofins 16%
Dr. MaxWell (+ Bacopa Ext) 120 Vcaps PB56510 Jan-23 150mg Zero NOW < 2%
Dr. MaxWell (+ Bacopa Ext) 120 Vcaps PB56510 Jan-23 150mg Zero NOW < 2%
Dr. MaxWell (+ Bacopa Ext) 120 Vcaps PB56510 Jan-23 150mg 1.7 mg Eurofins < 2%
GLS Nutrtition Formula/Earth Natural 200 Caps 11919 Aug-21 250mg/50mg 31.5 mg NOW 13%
Havasu Nutrition + Ginkgo 120mg 60 Caps 1019010 Oct-21 100mg/20% 58.8 mg NOW 59%
Havasu Nutrition + Ginkgo 120mg 60 Caps 1019010 Oct-21 100mg/20% 17.9 mg Eurofins 18%
Intelligent Labs 90 Vcaps PS55398 May-22 100mg 17.8 mg NOW 18%
Intelligent Labs 90 Vcaps PS55398 May-22 100mg 19.5 mg NOW 20%
Intelligent Labs 90 Vcaps PS55398 May-22 100mg 29 mg Eurofins 29%
longlifenutri (mislabeled*) 180 Vcaps 6175 Nov-22 250mg/20% 68 mg NOW 27%
longlifenutri (mislabeled*) 180 Vcaps 6156 Mar-23 250mg/20% 31.5 mg NOW 13%
longlifenutri (mislabeled*) 180 Vcaps 6156 Mar-23 250mg/20% 37.3 mg Eurofins 15%
Mental Refreshment (+ Formula) 200 Caps 16012005 Feb-22 167mg 136.8mg NOW 82%
Mental Refreshment (+ Formula) 100 Caps 22012005 Mar-22 167mg 47.3 mg Eurofins 28%
Mono Herb (plus Flax Powder) 90 Vcaps 200mg Mar-22 200mg 13.2 mg NOW 7%
Mono Herb (plus Flax Powder) 90 Vcaps 200mg Mar-22 200mg 1.4 mg Eurofins < 2%
Naturebell (mislabeled*) 180 Caps A911NB2 Nov-21 200mg/20% 34 mg NOW 17%
Naturebell (mislabeled*) 180 Caps A002MB7 Feb-22 200mg/20% 28 mg NOW 14%
Naturebell (mislabeled*) 180 Caps A002MB7 Feb-22 200mg/20% 5.6 mg Eurofins 3%
Naturetition Formula*/Earth Natural 200 Caps 416-128 Apr-22 250mg/50mg 11.9 mg NOW 5%
Naturetition Formula*/Earth Natural 200 Caps 416-128 Apr-22 250mg/50mg 3.8 mg NOW < 2%
Naturetition Formula*/Earth Natural 200 Caps 416-128 Apr-22 250mg/50mg 2.3 mg Eurofins < 2%
NUSA (+ Formula) 200 Vcaps 2004023 Apr-23 250mg? 31.7 mg NOW 13%
NUSA (+ Formula) 200 Vcaps 2004023 Apr-23 250mg? 2.4 mg Eurofins < 2%
Superior Health (+ Formula) 100 Caps 12041911 Aug-23 250mg 7 mg NOW 3%
Superior Health (+ Formula) 100 Caps 12041911 Aug-23 250mg 15.9 mg NOW 6%
Superior Health (+ Formula) 100 Caps 12041911 Aug-23 250mg 3.9 mg Eurofins < 2%
We Like Vitamins (+ Formula) 100 Caps 11101916 Nov-23 167mg 138.3 NOW 83%

For more information, visit www.nowfoods.com.

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