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Supplement Science


Evaluating Different Forms of Omega-3 Fatty Acids: Fish, Krill & Algae Oils

Omega fatty acids (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) are universally recognized for their importance to human health. This includes their value for cardiovascular health,1-5 joint health and mitigating inflammation,6-8 reducing UV-induced skin aging9-13 and a range of other issues. Now consider that, although guidelines recommend a combined DHA and EPA intake of between ...

Solubilized Keratin for Healthy Hair

From a consumer perspective, how important is having good hair? According to a survey1 of women, 29 percent of women reported feeling empowered by having good hair. Also, one in six women indicated that they would be embarrassed to go out in public if there’s something wrong with their hair, one in 10 said a ...

Black Ginger Extract for Abdominal Fat, Physical Fitness & Sexual Health

Black ginger (Kaempferia parviflora), a plant in the Zingiberaceae ginger family, is a traditional herbal medicine of Thailand. Black ginger should not be confused with common ginger (Zingiber officinale), which is in the same family but is a completely different genus and species. In any case the pharmacological properties of black ginger include anti-obesity, anti-inflammatory, ...

Nutraceutical Compensation for the Adverse Effects of GLP-1 Agonist Drugs

The use of GLP-1 agonist drugs—particularly for weight loss—are trending in a huge way. According to a new report,1 GLP-1s were the best-selling drug class in 2024, with approximately $50 billion in annual sales, and forecasted to surpass $100 billion by 2029 with an astounding compound annual growth rate of 19.2 percent. Certainly, anyone who ...

Polyamines for Cognitive Performance, Healthy Hair and More

Polyamines, including spermidine, spermine and putrescine, are synthesized in every living cell and are contained in many foods. They have many physiological activities, such as antioxidant and anti-inflammatory properties, cell and gene protection, and autophagy activation. They also have multiple demonstrated applications for health and wellness, including healthy aging,1-4 cognitive health,5-7 hair health8,9 and hormonal ...

NAC and Glycine: The Efficient Way to Raise Glutathione

The antioxidant glutathione (GSH) is a tripeptide1,2 primarily synthesized in the liver and composed of the amino acids cysteine, glutamic acid and glycine.3,4 It may be argued that GSH is the most important tripeptide in the body, playing critical roles in the synthesis and repair of DNA and protein, as well as the synthesis of ...

Vitamin K1 & K2 as MK-7 & MK-4: Differences & Applications

Vitamin K, particularly vitamin K2, represents a significant segment of the vitamin market. In fact, the global vitamin K2 market size was estimated at $421.1 million in 2023 and is projected to grow at a CAGR of 10.8 percent from 2024 to 2030.1 Certainly, vitamin K2 as menaquinone-7 (MK-7) has been recognized for its role ...

The Prebiotic Benefits of Acacia Gum and Baobab Fibers

If you’ve been part of the dietary supplement industry for the past few years, you will certainly have seen the increased popularity of the biotics market (pre-, pro- and postbiotics). In particular, prebiotics have seen significant growth, with a global valuation of $6.67 billion in 2023, and an expected compound annual growth rate of 6.3 ...

SNEDS: The Ultimate Delivery System for Nutraceuticals

Nutraceuticals, including compounds such as resveratrol, berberine, curcumin and ellagic acid, etc., have gained popularity over the past several decades for their potential health benefits. However, despite their promise, poor nutrient bioavailability has remained a major challenge in effectively harnessing their therapeutic potential. This article will examine the issues surrounding poor nutraceutical bioavailability, including the ...

Synthetic Melatonin vs. Phytomelatonin: The Scientific Difference

Are natural source nutraceuticals better than the synthetic version? The honest answer is sometimes yes, sometimes no. It really depends on whether the science on that nutraceutical can show a demonstrable difference. For most of the time melatonin has been on the market there has really been no opportunity to answer this question since synthetic ...

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