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Supplement Science


Phytomelatonin: Results of Human Clinical Research

In June of 2024 I wrote an article for Vitamin Retailer called, “Synthetic Melatonin vs. Phytomelatonin: The Scientific Difference,” in which I made a case for the advantages of plant-sourced phytomelatonin over conventional, synthetic melatonin. Since then, there have been studies on phytomelatonin from two different sources, expanding upon my earlier argument. That is what ...

A Lactobacillus acidophilus Postbiotic for Allergy, Skin Health & Immune Health Support

Regular readers of my “Supplement Science” column may notice that this is the third postbiotic article I’ve written for Vitamin Retailer over the past few years—the other two being “Akkermansia muciniphila: A GLP-1 Promoting Postbiotic for Weight Loss” and “A Lactobacillus plantarum postbiotic for Immunity.” Considering that the market for postbiotics, the newest of the ...

Biohacking Longevity: Nutrigenomic Targets with Proven Nutraceuticals – Part 2

In Part 1 of “Biohacking Longevity: Nutrigenomic Targets with Proven Nutraceuticals,” which was published in the January issue, I discussed concepts related to “biohacking” and “longevity,” including flipping your genetic switches, longevity, gene expression and nutrigenomics. I also discussed the impact of spermidine as an evidence-based nutraceutical that helps biohack longevity. In Part 2, this ...

Biohacking Longevity: Nutrigenomic Targets with Proven Nutraceuticals – Part 1

“Biohacking” and “longevity” are two popular buzzwords in the dietary supplement industry, while the term “nutrigenomic” is less known. Nevertheless, they all work together to achieve one of the most important nutraceutical strategies available for helping to put more years in your life and life in your years. This was a topic I presented at ...

Autophagy & Senescence for Healthy Aging: The Role of Spermidine Fisetin

This article is about autophagy and senescence, critical biological processes, and their roles in aging, health and wellness. It’s also about spermidine and fisetin, two naturally occurring compounds, and their role in promoting autophagy and reducing senescence. Let’s start with autophagy. Autophagy Autophagy (pronounced “ah-TAH-fah-gee”) is the body’s process of breaking down old and damaged ...

A Blast From the Past: The Surprising Benefits of Bitters

Digestive bitters—or just “bitters” for short—have a long history of use in herbal medicine for promoting digestion. But is there any real science supporting the use of bitter herbs for this purpose? This article will examine the history and science of bitters. Introduction to Bitters Bitters are substances found in a variety of herbs, and ...

Nutraceuticals for Autism Spectrum Disorder

According to the Centers for Disease Control and Prevention (CDC), about one in 36 children have been identified with autism spectrum disorder (ASD).1 That statistic includes my son who has Asperger’s syndrome, an ASD. Although he is now a high functioning 26-year-old man who effectively manages his Asperger’s, it was a bit of a bumpy ...

The Case For L-5-methyltetrahydrofolate Over Folic Acid

Folic acid can reduce the incidence of certain birth defects (i.e., neural tube defects) of the brain and spinal cord by more than 70 percent,1 and the fortification of our food supply with folic acid has done much to help achieve this accomplishment. Nevertheless, there are potentially negative issues associated with folic acid intake for ...

The Various Forms of Magnesium: Good, Better, Best

In May of 2013, I wrote an article for Vitamin Retailer titled, “Magnesium: A Mineral With Multiple Applications.” At that time, magnesium was already a trending nutraceutical in the dietary supplement industry—but that was only the beginning. In 2024 the magnesium market size was valued at $29.3 billion with estimations to reach $40.8 billion by ...

Akkermansia muciniphila: A GLP-1 Promoting Postbiotic for Weight Loss

Biotics are a significant category of interest in the dietary supplement industry, with postbiotics being the most recent inductee to join the ranks of pre- and probiotics. Although their introduction to the industry was only about a decade or so ago, the postbiotic supplements market was valued at $1.6 billion in 2021,1 and estimated to ...

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