Vitamin Retailer reached out to Katie Emerson, MS, RD, LDN, Manager of Scientific Affairs for Saddle Brook, NJ-based Nutrition21 (nutrition21.com) for her quick thoughts about the science behind newer applications for cognitive health.
VR: Considering newer applications and formulas for existing ingredients and compounds—such as magnesium, trace minerals, arginine, inositol, garlic, ginseng, even hemp—what is their science and market potential for cognitive health?
Emerson: As mentioned, nooLVL is a patented complex of Bonded Arginine and Silicon with an optimized dose of Inositol. It works FAST (in 15 minutes!) and safely delivers increased energy1, without increasing heart rate or blood pressure.
Nutrition21 recently conducted multiple computer-based cognitive tests through the online platform Cambridge Brain Sciences to study the effects of nooLVL in esports gamers. The tests produced significant results that back previous findings involving gamers and nooLVL.
Previous nooLVL Findings:
nooLVL was the first esports ingredient to be clinically studied in gamers. A 2019, double-blind, placebo-controlled trial found nooLVL significantly increases mental acuity and focus2 within 15 minutes. It also showed that nooLVL significantly improves accuracy (reduces errors), as well as attention and reaction time in gamers, even after 60 minutes of gaming2.
New Study: Tests & Results
To support existing studies on the effects of nooLVL, the new study presented at the Experimental Biology 2022 conference examined healthy adult males and females, aged 18–32, who received 1600 mg of nooLVL per day for seven days. Each subject was asked to take multiple computer-based cognitive performance tests prior to supplementation, at baseline, the first day after baseline, and on day seven after supplementation. These tests were designed to show how nooLVL influences the cognitive abilities and performance of esports gamers.
Results showed that nooLVL led to:3
• Significant improvement from baseline to day one, baseline to day seven, and day one to day seven was found on measures of attention/concentration (Double Trouble Stroop Test.)
• Significant improvement from baseline to day one and baseline to day seven was found in visual representation (Mental Rotation Test.)
• Significant improvement from baseline to day seven was found in forethought/sequencing (Spatial Planning Test.)1
References:
1. Perceived energy measured by the validated Profile of Mood States (POMS) questionnaire
2. Results compared to baseline.
3. No significant differences were found with the visual perception (Feature Match), object relationship (Polygons), or deductive reasoning (Odd One Out) tests.
Relevant Studies on nooLVL
• Emerson K, Perez Ojalvo S, Greenberg D. Effects of a Bonded Arginine Silicate Inositol combination (nooLVL) on Cognitive function in esports Gamers. The FASEB Journal. 2022;36(S1).
• Tartar JL, Kalman D, Hewlings S. A Prospective Study Evaluating the Effects of a Nutritional Supplement Intervention on Cognition, Mood States, and Mental Performance in Video Gamers. Nutrients. 2019;11(10):2326.
Feature
Vitamin Retailer reached out to Katie Emerson, MS, RD, LDN, Manager of Scientific Affairs for Saddle Brook, NJ-based Nutrition21 (
nutrition21.com) for her quick thoughts about the science behind newer applications for cognitive health.
VR: Considering newer applications and formulas for existing ingredients and compounds—such as magnesium, trace minerals, arginine, inositol, garlic, ginseng, even hemp—what is their science and market potential for cognitive health?
Emerson: As mentioned, nooLVL is a patented complex of Bonded Arginine and Silicon with an optimized dose of Inositol. It works FAST (in 15 minutes!) and safely delivers increased energy1, without increasing heart rate or blood pressure.
Nutrition21 recently conducted multiple computer-based cognitive tests through the online platform Cambridge Brain Sciences to study the effects of nooLVL in esports gamers. The tests produced significant results that back previous findings involving gamers and nooLVL.
Previous nooLVL Findings:
nooLVL was the first esports ingredient to be clinically studied in gamers. A 2019, double-blind, placebo-controlled trial found nooLVL significantly increases mental acuity and focus2 within 15 minutes. It also showed that nooLVL significantly improves accuracy (reduces errors), as well as attention and reaction time in gamers, even after 60 minutes of gaming2.
New Study: Tests & Results
To support existing studies on the effects of nooLVL, the new study presented at the Experimental Biology 2022 conference examined healthy adult males and females, aged 18–32, who received 1600 mg of nooLVL per day for seven days. Each subject was asked to take multiple computer-based cognitive performance tests prior to supplementation, at baseline, the first day after baseline, and on day seven after supplementation. These tests were designed to show how nooLVL influences the cognitive abilities and performance of esports gamers.
Results showed that nooLVL led to:3
• Significant improvement from baseline to day one, baseline to day seven, and day one to day seven was found on measures of attention/concentration (Double Trouble Stroop Test.)
• Significant improvement from baseline to day one and baseline to day seven was found in visual representation (Mental Rotation Test.)
• Significant improvement from baseline to day seven was found in forethought/sequencing (Spatial Planning Test.)1
References:
1. Perceived energy measured by the validated Profile of Mood States (POMS) questionnaire
2. Results compared to baseline.
3. No significant differences were found with the visual perception (Feature Match), object relationship (Polygons), or deductive reasoning (Odd One Out) tests.
Relevant Studies on nooLVL
• Emerson K, Perez Ojalvo S, Greenberg D. Effects of a Bonded Arginine Silicate Inositol combination (nooLVL) on Cognitive function in esports Gamers. The FASEB Journal. 2022;36(S1).
• Tartar JL, Kalman D, Hewlings S. A Prospective Study Evaluating the Effects of a Nutritional Supplement Intervention on Cognition, Mood States, and Mental Performance in Video Gamers. Nutrients. 2019;11(10):2326.
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