Florida-based Bio-Kult, a research-based probiotic, announced new clinical trial research confirming that the use of its multi-strain probiotic (14 different bacterial strains; 8 billion colony-forming units per day) is safe and superior to placebo in improving GI (gastrointestinal) symptoms over a period of four months in patients with IBS-D (diarrhea-predominant irritable bowel syndrome).
In the largest ever double-blind randomized controlled trial of probiotic supplements in IBS-diarrhea type patients ever conducted (according to the company), dramatic improvements in symptoms were reported.
In the study of 360 patients who had IBS with diarrhea as their predominant symptom (IBS-D), those patients who took the probiotic supplement Bio-Kult reported a 69 percent decrease in abdominal pain, compared to 47 percent in a group who took a placebo.
The four-month study conducted by the University of Bangabandhu Sheikh Mujib Medical University in Dhaka, Bangladesh also found that the number of patients who rated their symptoms as moderate to severe at the beginning of the study was reduced by 86 percent in the Bio-Kult group, compared to 52 percent in those who took a placebo. A total of 33.7 percent in the Bio-Kult group reported that all their symptoms had disappeared at the end of the 16 weeks compared to just 12.8 percent in the placebo group.
In addition to relieving IBS-D symptoms, Bio-Kult was also shown to markedly improve all aspects of quality of life (QoL) evaluated using a 34-point IBS-QoL questionnaire. These included psychological issues such as anxiety about health, depression, lack of enjoyment of life and feelings of having to avoid stressful situations.
For more information, visit www.bio-kult.com.