7-hydroxymitragynine
FDA and DOJ Seize 7-OH Products in Missouri
In December 2025, the U.S Food and Drug Administration (FDA) and the U.S. Department of Justice (DOJ) seized approximately 73,000 units of 7-hydroxymitragynine (7-OH) products—valued at about $1 million—from three firms in Missouri. The seizure focused on foods and dietary supplements products—including liquid shots and tablets—that contain 7-OH as an ingredient. Concentrated 7-OH has been ...
Florida Attorney General Files Emergency Rule on 7-OH Products
On Aug. 13, Florida Attorney General James Uthmeier filed an emergency rule to classify isolated and/or concentrated 7-hydroxymitragynine (7-OH) products as a Schedule I controlled substance in Florida. The rule takes effect immediately and makes it illegal to sell, possess or distribute any isolated form of 7-OH in the state. The announcement comes a ...
FDA Takes Steps to Restrict 7-OH Opioid Products
On July 29, the U.S. Food and Drug Administration (FDA) took “bold steps” to protect American consumers from dangerous illegal opioids. The agency recommended a scheduling action to control certain 7-hydroxymitragyine (7-OH) products under the Controlled Substances Act. According to FDA, 7-OH is increasingly recognized for numerous health and safety issues because of its ability ...
FDA Issues Warning Letters on Products Containing 7-OH
On July 15, the U.S. Food and Drug Administration (FDA) announced it sent seven warning letters to companies for “illegally marketing” products containing 7-hydroxymitragynine (7-OH). According to FDA, there is growing concern around “novel potent opioid products” that are being marketed and sold online and in smoke shops, gas stations and corner stores. 7-OH is ...
DEA Postpones Ban on Kratom
On August 31, 2016, the Drug Enforcement Administration (DEA) published in the Federal Register a notice of intent to temporarily place mitragynine and 7-hydroxymitragynine, which are the main psychoactive constituents of the plant Mitragyna speciosa, also referred to as kratom, into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances Act. Since ...
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